Anadrol Review : Its Benefits and Side Effects

Oxymetholone is sold under several brand names including Anadrol and Anapolon among others. It is an androgenic and anabolic steroid, primarily created for the treatment of anaemia.

Due to its effectiveness, it is also used in the treatment of some symptoms of HIV/AIDS and osteoporosis since it improves weight gain and muscle growth.

It was first created in 1959 and in 1961, it was accepted for medical use. Aside from medical use, it is radically used for performance and physical improvements.

After its approval for medical use, Parke Davis & Co started manufacturing Oxymetholone under the name Adroyd while the pharmaceutical company, Syntex, marketed under the brand name Anadrol-50.

Despite the positive aspects of Anadrol (Oxymetholone) has an ugly effect on the liver and many other side effects.

The effectiveness of Anadrol is mostly compared to that of Dianabol (Methandrostenolone) because they contain similar compounds but they have some stark differences.

Today, Anadrol has become very popular as a red blood cell booster by increasing haemoglobin production.

This is achieved because, just like other anabolic steroids, Anadrol enhances the erythropoiesis (red blood cell generation) process in the body.

Anadrol has gained fame in the bodybuilding and athletic fields because of its potential to increase protein synthesis thereby promoting body mass generation.

Is it Legal?

The use of anabolic steroids and its legality differs from country to country. Anadrol use is legal in countries like the UK, Canada, and the US, but these countries forbid illegal trafficking.

You may have to check if your country allows its use to avoid being caught up with the law.

Properties of Anadrol

Anadrol is among the anabolic steroids compounds called Dihydrotestosterone (DHT) derivatives. DHT is an androgen produced naturally in the human body. This makes Anadrol a modification of DTH.

Other anabolic steroids within this family are the Winstrol (Stanozolol), Masteron (Drostanolone), Anavar (Oxandrolone), and Primobolan (Methenolone).

All the mentions anabolic therefore share similar characteristics.

However, Anadrol is in the methylated group of DHT containing 2-hydroxymethylene group bound to a carbon atom located in the first cycloalkane ring of the overall structure of the steroid molecule.

As such Anadrol has a high degree of active life in the muscle tissue compared to its father compound, DHT.

Once DHT enters the system, it is broken down by enzymes 3-hydroxysteroid dehydrogenase. But the comparison and the modification of Anadrol, allows it to swerve the normal pathway, and therefore remains in its original form when it enters the muscle tissues.

This makes it able to perform its biological role in the body. Anodrol has certain behaviours different from that of other DHT’s.

This includes exhibiting some level of estrogenic effects in the body, which is contrary to the properties of DHT.

DHT modifications are originally not supposed to possess estrogenic effect since it cannot convert into estrogen in the body.

Effects on the Liver

The main problem with Anadrol is its hepatotoxicity (toxic to the liver). Its alkylated content is 17th carbon also called (C17 Alpha Alkylation, or methylation).

This allows it to survive metabolism in the liver when administered orally. This puts a stress on the liver and is considered by many as the most toxic anabolic steroids.

Comparison with Testosterone

The anabolic rating of Anadrol is 320, making it 3.2 times stronger than testosterone. Comparing their androgenic effects, Anadrol has proven to produce less androgenic effect compared to testosterone.

It has a rate of 45 compared to testosterone’s 100.


Oxymetholone (AKA Anadrol, Anadrol-50, Adrol)

Chemical Name: (17 beta-hydroxy-2-hydroxymethylene-17alpha-methyl-5 alpha-androstan-3-one)

Molecular Weight: 332.48 g/mol

Formula: C21H32O3

Original Manufacturer: Syntex

Half Life: 8 – 9 hours

Detection Time: 2 months

Anabolic Rating: 320

Androgenic Rating: 45 

Side Effects

Like many other anabolic steroids, Anadrol also comes with some side effects and you must take critical considerations of it before choosing to use the product.


Side effects of Anadrol include:


  • Having increased sexual appetite
  • Increase in growth of hair on the body
  • Some people may experience the change in voice
  • Developing skin conditions like acne
  • Prolong use can damage the liver
  • It has a very strong anabolic effect but weak androgenic effects.

The most radically side effect is liver toxicity as already mentioned. This makes Anadrol mostly regarded as one of the worst orally administered anabolic steroids. You should, therefore, be cautious when taking it.

Would you prefer high performance and strength to the health of your liver? It is therefore advisable not to take it more than 4 to 6 weeks while taking other supplements that improve the health of the liver.

The estrogenic side effects of Anadrol are water retention, bloating, and an increase in blood pressure. It can also trigger gynecomastia effects.

These effects can be reduced through the use of SERM (Selective Estrogen Receptor Modulator), such as Nolvadex (Tamoxifen). This can reduce some of the gynecomastia side effects excluding bloating and retention.

Anadrol also has some cardiovascular effects, just like another anabolic steroid.

Uses and Benefits

Anadrol has several benefits despite its other negative effects.

  • It helps in mass gain, improving your strength, bulking, and weight gain.
  • Anadrol also helps in fat loss but many people do not administer it for such purposes because of the ability to increase weight gain.

It is not advisable to use if you want to achieve a cut or chiselled look since because of its water retention ability.

It can be used to treat anaemia that is by increasing the production of red blood cell.


Anadrol is administered orally as prescribed by the doctor. You have to be consistent with its use to achieve the intended purpose.


As with the other anabolic steroid, an overdose or misuse of Anadrol can be detrimental to your health. You can have effects like heart attack, stroke, mood swing, and other diseases when overused.

If you start experiences such effects discontinue its use.

How to Buy

You can purchase Anadrol online through trusted sites. This makes obtaining it very easy.

You can have it in two grades, underground lab (UGL) grade products, and pharmaceutical grade products manufactured by legitimate pharmaceutical companies.